This research aims to investigate the current status and future direction of the use of information systems for supply chain management for companies with multicomponent production. Paper presents a qualitative research method for analyzing a supply chain processes and for identifying ways of its information support. Based on data collected from different enterprises, can be concluded that in order to identify the most effective strategies of information support of supply chain the attention should focus on the identification and management of the sources of uncertainties, risks and cyber security. To successfully integrate business processes between suppliers and customers, manufacturers must solve the complex problem of information security. The main practical results are: proposed a new approach to the identification and prediction of supply risk within uncertainties conditions; proposed a complex solution to secure data in information systems for supply chain management.